After a three-month absence, The Atom Rooms was restored on Monday 2 April to the North Wall of Portobello Road.
The 40 panel, 100m artwork, which was removed in January following a spate of vandalism, will now remain in situ until August 2012.
The installation forms part of the Council's Portobello Road Arts Project, a series of temporary public art commissions for the North Wall, which is on the stretch of road that links Portobello and Golborne markets.
The Atom Rooms is the fifth in the series and replicates the work of artists formerly exhibited at the nearby gallery of the same name.
Among other things, the Portobello Road Arts Project aims to promote the work of local artists and encourage visitors to continue their journeys up the Portobello Road so that they discover the lesser known but equally vibrant Golborne market.
Commenting on the restoration, the Deputy Leader of the Council, Cllr Nick Paget-Brown, said: "The Council has never given into vandals and we are not going to start now.
"We are going to continue to showcase our emerging young artists and provide beauty and visual interest at every opportunity."